This is a rare autosomal recessive condition featuring pigmentary retinal degeneration, sensorineural hearing loss, diabetes, obesity and various other symptoms. The gene has been localised to chromosome 2p. The laboratory in Maine, United States, would like to contact any affected families. Contact Dr Jan Marsall at Fax 091 207 288 6078 or The Jackson Laboratory, 600 Main Street, Bar Harbour, Maine USA 04609. E-mail jdm@aretha.jax.org.